Despite the identification of the gene responsible for Huntington’s disease (HD) 25 years ago, there is not yet an effective treatment to slow or stop the progression of symptoms. While remarkable advances in HD biology have been made using animal models, the development of effective therapies requires research in humans. 

As a result, the Huntington’s Disease Society of America has adopted a patient-centric research strategy to push the HD field closer to slowing progression and onset. HDSA’s Human Biology Project is the cornerstone of this strategy, with the aim of better understanding the biology of Huntington’s disease as it occurs in humans.  

Since 2013, HDSA has committed over $5 million to support this program. Today, HDSA is proud to announce the 2021 Request for Proposals for the HD Human Biology Project.