Despite the identification of the gene responsible for Huntington’s disease (HD) over 30 years ago, there is not yet an effective treatment to slow or stop the progression of symptoms. While remarkable advances in HD biology have been made using animal models, the development of effective therapies requires research in humans. 

    

As a result, the Huntington’s Disease Society of America has adopted a patient-centric research strategy to push the HD field closer to slowing progression and onset. HDSA’s HD Human Biology Project is the cornerstone of this strategy, with the aim of better understanding the biology of Huntington’s disease as it occurs in humans.  

 

Since 2013, HDSA has committed over $9 million to support this program. Today, HDSA is proud to announce the 2025 Request for Proposals for the HD Human Biology Project. 

  

What Is This Project?  

A one- or two-year grant mechanism to provide support for young scientists and clinicians to work collaboratively with HD clinics from around the world. Awards up to $90,000/year (up to $72,000 salary support and $30,000 research budget).  

  

Who Can Apply? 

Open to researchers from around the world regardless of position/title. Preference given to young investigators (PhDs and MDs) who are not yet independent. Innovative ideas from non-scientists and applications from for-profit institutions are also accepted and encouraged. Applicants may propose to work with any HD clinic around the world to study HD patients, tissues, or cells.  

  

Due Dates 

Letter of Intent: June 13th, 2025 

Full Application: August 15th, 2025  

  

CLICK HERE TO LEARN MORE & APPLY 

 

Questions can be directed to Tamara Maiuri, PhD, Associate Director, Research & Patient Engagement, TMaiuri@hdsa.org, and Howlatu Sowe, Mission Program Coordinator, at HSowe@hdsa.org