Roy Maimon, PhD
Postdoctoral Fellow, University of California San Diego, Mentor: Dr. Don Cleveland
Identifying Mechanisms of Adult Neurogenesis by Exploiting Single Cell Spatial Transcriptomics and Application to HD
HD leads to loss of neurons, a type of brain cell that are not naturally renewed like other cells in the body. Dr. Maimon will work in the lab of Dr. Don Cleveland to employ a genetic drug which in mice can awaken dormant support cells in the brain and convert them into new neurons. He will now test this method in human cells and organoids. The project will further generate an important map of which genes in which brain areas can best be turned on and off to facilitate a healthier brain network.
This project is generously supported by the Bev Hartig Huntington’s Disease Foundation, https://bevhartighuntingtonsdisease.com/