Jessica Levesley, PhD

Postdoctoral Research Fellow, University of British Columbia, Mentor: Dr. Michael Hayden

Investigation of the effect and mechanistic drivers of loss of interruption modifier variants in Huntington disease patients

Dr. Levesley will work in the lab of Dr. Michael Hayden to examine a rare set of HD brain tissue containing a DNA variation at the start of the huntingtin gene that has been linked to earlier onset of symptoms of the disease. The goal of her project is to better understand why this genetic change causes earlier onset and to find targets for future therapies to delay symptoms of the disease.