Zachariah McLean, PhD

Research Fellow in Neurology, Massachusetts General Hospital , Dr. James Gusella


Unraveling Huntington's Disease pathogenesis: Investigating Repeat Expansion and Genetic Modifiers Using Advanced Cell Models

Dr. McLean is developing a cell model that closely resembles what happens in the brains of people with HD. Using this, he will test how different genetic factors affect further expansion of the gene that causes HD, which is thought to influence disease progression.